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Each of the 20 drugs in history that have sold for more than $50 billion can make you rich
Source:药事纵横 | Author:pro954f45 | Published time: 2018-04-14 | 1710 Views | Share:
The preface
      The 1990s were a golden age for the rapid development of innovative drugs. Many blockbuster products were born in that era, and many pharmaceutical giants were formed in that era. The author based on the interest and hobby of the statistics of the global drug sales, and the establishment of a drug database. By comparing and filtering the data, we came up with 20 super bombshells with cumulative sales of more than $50 billion. However, this article is not to take stock of these super blockbuster, the author's purpose is to reverse through these blockbuster to study the process and operation mode of each big pharmaceutical giant. This article is an opinion article, just for reference.
       1. Lipitor (atorvastatin), with cumulative sales of $152.3 billion
      In the 1970s, Japanese scholars cultivated aspergillus roxb to obtain lovastatin, thus opening the chapter of the inhibitor of hfg-coa reductase. Because of its superior lipid-lowering effect and small adverse reactions, statins quickly became a hot topic in research. Since lovastatin was approved in 1987, the FDA has approved simvastatin, pivastatin, and fluvastatin, and atorvastatin is the fifth hmg-coa reductase inhibitor approved by the FDA. Lipitor was approved in December 1996, listed in early 1997, and reached its peak sales of $13.83 billion in 2006. So far, lipitor has generated $152.3 billion in revenue for Pfizer.